http://blogs.jwatch.org/hiv-id-observations/index.php/back-to-school-top-questions-from-id-in-primary-care/2013/10/18/?query=pfw-featured
Above is an article from the entertaining and useful, non academic knowledged Paul Sax, an infectious disease specialist with the excellent Journal Watch ID blog. The above link outlines that despite some influential texts ( Sanfords, and even my beloved Tarascons) listing standard treatment for CA-MRSA to be two Bactrim DS tabs bid, that this may well be "urban legend" and one can safely get by with the more frequent, UTI-like one tab by mouth bid.
While I would usually say in these skin abscess cases to simply use doxycycline, as many of you all know the pharmaceutical companies have found a way to remove doxy from the "$4 dollar drug list" and it is now much, much more expensive. As such, Bactrim DS has become my main gunner for CA-MRSA lesions.
As Sax mentioned, this 2 tablet bid dosing leads to heinous nausea and patient non compliance. The medicine cannot heal if the patient is non complaint.
Do you use the 2 tab bid dosing? Or, has too many patient call backs triggered you to return to the one tab bid?
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